Pediatric

Corticosteroids may cause infections such as chickenpox or measles to be more serious in children who catch them. These medicines can also slow or stop growth in children and in growing teenagers, especially when they are used for a long time. Before this medicine is given to children or teenagers, you should discuss its use with your child's doctor and then carefully follow the doctor's instructions.

Geriatric

Older patients may be more likely to develop high blood pressure or osteoporosis (bone disease) from corticosteroids. Women are especially at risk of developing bone disease.

Pregnancy

Studies on birth defects with corticosteroids have not been done in humans. However, studies in animals have shown that corticosteroids cause birth defects

Breastfeeding

Corticosteroids pass into breast milk and may cause problems with growth or other unwanted effects in nursing babies. Depending on the amount of medicine you are taking every day, it may be necessary for you to take another medicine or to stop breast-feeding during treatment.

Drug Interactions

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aldesleukin
• Asparaginase
• Atazanavir
• Bupropion
• Clarithromycin
• Darunavir
• Dasatinib
• Etravirine
• Fluindione
• Fosamprenavir
• Gatifloxacin
• Imatinib
• Indinavir
• Itraconazole
• Ixabepilone
• Ketoconazole
• Lapatinib
• Nefazodone
• Nelfinavir
• Nilotinib
• Quetiapine
• Ritonavir
• Saquinavir
• Sunitinib
• Telithromycin
• Temsirolimus
• Thalidomide
• Tipranavir

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Acquired immunodeficiency syndrome (AIDS) or
• Fungus infection or
• Herpes simplex infection of the eye or
• Human immunodeficiency virus (HIV) infection or
• Infection at the place of treatment or
• Other infection or
• Recent surgery or serious injury or
• Strongyloides (worm) infestation or
• Tuberculosis (active TB, nonactive TB, or past history of)—Corticosteroids can cause slower healing, worsen existing infections, or cause new infections.

• Chickenpox (including recent exposure) or
• Measles (including recent exposure)—Risk of severe disease affecting other parts of the body.

• Diabetes mellitus (sugar diabetes)—Corticosteroids may cause a loss of control of diabetes by increasing blood glucose (sugar).
  
   
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